Neither objectively better. Right one depends on style, body, preferences.
Position
Cruiser: feet forward, upright, neutral hands. Comfortable, low seat. Sport: feet back, torso leaned, low hands. Aerodynamic but wrists/back on long rides.
Comfort
Cruisers win for most. Relaxed position, wind protection options, luggage. Sport-touring bikes split the difference.
Performance
Sport: light, powerful, agile. Incredible on twisty roads. Cruiser: heavier, stability-focused. Confidence-inspiring on open roads.
Maintenance/Cost
Cruisers: longer intervals, simpler engines. Sport: more frequent (chains, valves, tires). Insurance higher for sport.
Resale
Harley/Indian hold value. Japanese cruisers depreciate more but cost less. Sport bikes depreciate faster early.
Choose
Ride both if possible. If between them, consider a standard/naked bike: neutral position, sport performance, cruiser comfort.